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High-throughput stability analyzer TURBISCAN AGS

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High-throughput stability analyzer TURBISCAN AGS The World Leader in Stability Analysis

  • Accelerated destabilization detection – up to 1,000 x faster than visual observation thanks to SMLS
  • Real stability: sample stability analysis without the need for dilution or mechanical stress, in concentrations up to 95%
  • Fully automated robot station, working 24/7 without any user intervention
  • 3 thermo-controlled storage racks (from RT to 60°C) to simulate storage conditions and accelerate even more stability evaluations
  • Quantitative measurements of dispersion stability and shelf-life, migration velocity, particle size diameter, and other parameters
  • One-click stability ranking with the TURBISCAN Stability Index
  • Analyze up to 54 samples
砂

エマルション

  • Cosmetic creams and lotions
  • Dairy products and beverages, flavor emulsions
  • Pharmaceutical parenteral and topical forms
  • Metalworking fluids
  • Agrochemical: fertilizers, pesticides, ...
  • Petroleum emulsion
医薬品

サスペンション

  • Paints, inks, and coatings
  • Drug & and vaccine suspension
  • Make-up and sunscreen
  • Chemical & polymer industry
  • Ceramics and catalysts
  • Battery slurries
  • Electronic slurries
砂糖

コロイド粒子 & ナノ粒子

  • Drug delivery system: LNP, Liposomes, ...
  • Research on nanoparticles and nanoparticle suspension
  • Polymer and biopolymer dispersion

    その他

Fast Detection of Settling Particles Sedimentation

The TURBISCAN technology offers a significantly faster (up to 1,000 times) and more reliable detection of sedimentation compared to visual observation. Furthermore, naked-eye observation makes it difficult to calculate the migration rate and is prone to error and misinterpretation. In contrast, the TURBISCAN technology provides a fast and non-destructive way to detect and quantify sedimentation and particle size over time and can detect even small changes in highly concentrated samples without any dilution or mechanical stress. This makes it ideal for analyzing complex suspensions and formulations, and getting a quicker, reliable, and more accurate answer on sedimentation monitoring. 

正確な粒子長の測定

Fast Detection of Droplet Migration Creaming of Emulsions

When it comes to measuring droplet migration and creaming behavior in emulsion systems, the TURBISCAN technology has several advantages for formulators. On one hand, it provides a fast measurement (up to 1,000 times faster than visual observation) of native samples and a non-destructive way to detect and measure droplet migration. On the other hand, the migration rate can easily be determined and helps the formulator to compare formulas, making it ideal for analyzing complex emulsions with a wide range of droplet sizes and concentrations. Additionally, the TURBISCAN technology provides insights into the mechanisms driving droplet migration, which can be used to improve formulation and processing conditions. Overall, the use of TURBISCAN technology in emulsion analysis leads to faster, more accurate, and more reliable results compared to traditional methods.

不適合粒子の識別

Save Time to Measure Physical Stability Formulation: Stability Measurement and Shelf-Life Estimation

The TURBISCAN has been extensively used to measure the physical stability of formulations and colloidal systems. This technology helps the formulator to save time and precisely rank and quantify the samples’ stability in different trials or batches. It applies to native samples, even on very highly concentrated formulations. Not only saving time, the TURBISCAN also provides destabilization speed and metrics as well as robust analytics to make shelf-life predictions. The TURBISCAN technology complies perfectly with ISO TR13097 recommendations and is ideal when it comes to quickly and accurately measuring stability. Stop the guesswork and make decisions based on facts!

3D解析の有効性

What Can Be Measured Can Also Be Improved Stability Mapping: Emulsions and Suspensions

Measuring the stability of emulsions and formulations is traditionally done by visual observations. In addition to being long and tedious, the visual inspection of emulsion destabilization usually ends up with a pass / fail answer. This is suboptimal for fine-tuning the ideal concentration of surfactants or stabilizers to be added to reach the desired shelf-life. The TURBISCAN is a great help in this regard; not only does it save a huge amount of time to detect the destabilization, but it also provides a value based on the instability and ranks different formulas as a function of their shelf-life. It hence produces objective and repeatable data to make a better, greener, and safer product.

高吸水性樹脂
高吸水性樹脂

Stable Products for Safer and More Efficient Pharmaceutical Suspensions Vaccine and Parenteral Dispersions

Stability and shelf-life testing are essential for pharmaceutical products and drugs. Destabilization or instabilities in vaccines, parenteral dispersions, or pharmaceutical products can have a major impact on product efficacy, and in some cases, on patient safety. While many techniques are available, the TURBISCAN offers in-situ, non-dilution, and non-destructive measurements to detect destabilization and save time therein. It provides a clear, precise, and objective stability measurement, essential to making fast and right decisions in R&D or quality control. The TURBISCAN has been intensively used to study the stability and redispersion capability of vaccines, as well as of parenteral and injectable dispersions and providing scientists with a deep insight into the dispersion state and its evolution.

光反射ビーズの粒子形状評価

Homogenous Slurries for Higher Battery Performance Improving Battery Efficiency

There is an exponential demand for energy storage and batteries, either to cover our need for mobility and communication or to match environmental challenges. Lithium-ion batteries are the most widely used technology, and one of the key steps in developing and manufacturing them is the slurry formulation (used on the electrodes), ensuring the final battery quality. This slurry is usually highly concentrated and dark (due to a high concentration of carbon black) and using conventional light scattering techniques for evaluation is challenging or requires an important amount of dilution. The TURBISCAN has been successfully used to monitor the stability of these slurries and helps the formulator to optimize the formulation, test the production, and identify new raw materials.

High Resolution Size Measurement

Secure Your Data Collection TURBISOFT AGS Software for TURBISCAN AGS

When dealing with high-throughput analysis, software is essential to generate and treat all the data generated. The TURBISCAN AGS comes with 2 software packs: TURBISOFT AGS to secure your data collection as well as the sample handling, and TURBISOFT to interpret the data, compare the sample stability and generate reports. This offers the flexibility and freedom to acquire data and interpret the analysis on different computers and in different locations, all at the same time. TURBISOFT AGS has been designed for data acquisition, is user-friendly and only requires information to automatically start and run the analysis. TURBISOFT interprets and exports the results and has an intuitive and user-friendly interface to get the desired result with just a few clicks.

  • Intuitive and straightforward navigation
  • Fast and robust stability comparison thanks to the TSI algorithm
  • Advanced calculation for deep data analysis: migration rate, mean particle size evolution, phase separation, and more
  • Stay up to date: free license – free software updates
  • Need to use multiple computers? This multi-user software has you covered
  • Data export as easy as copy-paste
  • Video recording of sample destabilization for up to 6 samples
  • Fully guided calibration check-up procedure
 レチクル

Standard Vials (20 ml)

Cylindric glass vials have a recommended volume of approximately 20 ml. They are disposable to avoid chemical or bacterial contamination and decrease labor costs for washing and drying. The vials are closed thanks to a cap and a disposable PTFE seal to prevent evaporation in case of elevated temperature. These vials are meant to reproduce your visual stability test.

Audit Trail Manager

Robot Handling and Gripper

Robotic movement and sample grabbing have been fine-tuned for smooth and robust sample handling from the temperature chambers to the measurement units. The cycling time for a sample is less than a minute.

ガイド

Storage Racks

Between measurements, the samples are stored in temperature-controlled racks. The TURBISCAN AGS comes with 3 separate and independent sample racks and each be set from RT+5°C up to 60°C (optional: 90°C)

ガイド

Calibration Standards

Each TURBISCAN comes with a set of standards to check instrument calibration. The TURBISCAN software, TURBISOFT, guides you step by step and once the procedure is finished, the software gives an "Okay" signal. The test and results are saved, and the instrument checking procedure can be tracked.

ガイド

Particle Size Distribution

The TURBISIZE software can measure the distribution of particle size (ISO13317) and the distribution of migration speed for any data obtained with a TURBISCAN, without any need to dilute, prepare, or modify the sample.

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TURBISCAN AGS 製品仕様

Acquisition scan step40 µm
Automatic sample recognition (bar-code)あり
CE認証あり
寸法145 x 75 x 85 cm
関連規格ISO/TR 13097:2013, ISO/TR 18811:2018, ISO/TS 22107:2021, ISO/TS 21357:2022
Measured size range10 nm - 1 mm
測定原理Static Multiple Light Scattering (SMLS)
Number of Samples54
Reproducibility / Repeatability on latex standards+/- 0.05% / 0.05%
サンプル濃度0.0001 - 95% v/v
試料の量20 mL
ソフトウェアTurbisoft AGS
温度範囲RT - 60°C (3 racks) - 90°C on demand
重量50 kg

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